Review



src family tyrosine kinase inhibitor pp1  (Millipore)


Bioz Verified Symbol Millipore is a verified supplier  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    Millipore src family tyrosine kinase inhibitor pp1
    Src Family Tyrosine Kinase Inhibitor Pp1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/src+family+tyrosine+kinase+inhibitor+pp1/pm38242873-317-15-21
    Average 90 stars, based on 1 article reviews
    src family tyrosine kinase inhibitor pp1 - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    Isolation:

    Article Title: Poly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytes
    Article Snippet: .. PMN pre-treatment with Src family kinase inhibitor PP1 After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA) or an equivalent volume of dimethyl sulfoxide (Sigma-Aldrich, St. Louis, MO). ..

    Article Title: Poly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytes
    Article Snippet: .. After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA) or an equivalent volume of dimethyl sulfoxide (Sigma-Aldrich, St. Louis, MO). ..

    Article Title: Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release
    Article Snippet: .. PMN pre-treatment with Src family kinase inhibitor PP1 and/or PI3K-γ inhibitor AS604850 After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA), 1 μM PI3K-γ inhibitor AS604850 (Echelon Biosciences Inc., Salt Lake City, UT), or an equivalent volume of dimethyl sulfoxide (DMSO; Sigma–Aldrich, St. Louis, MO). ..

    Article Title: Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release
    Article Snippet: .. After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA), 1 μM PI3K-γ inhibitor AS604850 (Echelon Biosciences Inc., Salt Lake City, UT), or an equivalent volume of dimethyl sulfoxide (DMSO; Sigma–Aldrich, St. Louis, MO). ..

    Concentration Assay:

    Article Title: Poly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytes
    Article Snippet: .. PMN pre-treatment with Src family kinase inhibitor PP1 After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA) or an equivalent volume of dimethyl sulfoxide (Sigma-Aldrich, St. Louis, MO). ..

    Article Title: Poly(ethylene glycol)-containing hydrogels promote the release of primary granules from human blood-derived polymorphonuclear leukocytes
    Article Snippet: .. After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA) or an equivalent volume of dimethyl sulfoxide (Sigma-Aldrich, St. Louis, MO). ..

    Article Title: Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release
    Article Snippet: .. PMN pre-treatment with Src family kinase inhibitor PP1 and/or PI3K-γ inhibitor AS604850 After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA), 1 μM PI3K-γ inhibitor AS604850 (Echelon Biosciences Inc., Salt Lake City, UT), or an equivalent volume of dimethyl sulfoxide (DMSO; Sigma–Aldrich, St. Louis, MO). ..

    Article Title: Biomaterials differentially regulate Src kinases and phosphoinositide 3-kinase-γ in polymorphonuclear leukocyte primary and tertiary granule release
    Article Snippet: .. After isolation, PMNs were suspended at a concentration of 2 × 10 6 cells/ml in RPMI-1640 medium supplemented with 10% AHS and 10 μM Src family kinase inhibitor PP1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine; EMD Millipore, Billerica, MA), 1 μM PI3K-γ inhibitor AS604850 (Echelon Biosciences Inc., Salt Lake City, UT), or an equivalent volume of dimethyl sulfoxide (DMSO; Sigma–Aldrich, St. Louis, MO). ..



    Similar Products

    src family kinase inhibitors pp1  (Tocris)
    93
    Tocris src family kinase inhibitors pp1
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    Src Family Kinase Inhibitors Pp1, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/PP+1/pmc12372067-49-0-5
    Average 93 stars, based on 1 article reviews
    src family kinase inhibitors pp1 - by Bioz Stars, 2026-09
    93/100 stars
    		  Buy from Supplier
    src family tyrosine kinase inhibitor pp1  (Millipore)
    90
    Millipore src family tyrosine kinase inhibitor pp1
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    Src Family Tyrosine Kinase Inhibitor Pp1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/src+family+tyrosine+kinase+inhibitor+pp1/pm38242873-317-15-21
    Average 90 stars, based on 1 article reviews
    src family tyrosine kinase inhibitor pp1 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    src family tyrosine kinase inhibitors pp1  (Santa Cruz Biotechnology)
    91
    Santa Cruz Biotechnology src family tyrosine kinase inhibitors pp1
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    Src Family Tyrosine Kinase Inhibitors Pp1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/PP+1/pm37958964-299-6-27
    Average 91 stars, based on 1 article reviews
    src family tyrosine kinase inhibitors pp1 - by Bioz Stars, 2026-09
    91/100 stars
    		  Buy from Supplier
    pp1 (potent, selective src family kinase inhibitor  (Tocris)
    90
    Tocris pp1 (potent, selective src family kinase inhibitor
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    Pp1 (Potent, Selective Src Family Kinase Inhibitor, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/src+family+kinase+inhibitor+pp2/10__1021_slash_acs__jmedchem__0c00841-674-0-10
    Average 90 stars, based on 1 article reviews
    pp1 (potent, selective src family kinase inhibitor - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    the src family kinase inhibitor pp1  (Millipore)
    90
    Millipore the src family kinase inhibitor pp1
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    The Src Family Kinase Inhibitor Pp1, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/src+kinase+inhibitor+pp2/pmc07034189-30-6-13
    Average 90 stars, based on 1 article reviews
    the src family kinase inhibitor pp1 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    selective inhibitor src family tyrosine kinases, pp1  (Tocris)
    90
    Tocris selective inhibitor src family tyrosine kinases, pp1
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    Selective Inhibitor Src Family Tyrosine Kinases, Pp1, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/1-Naphthyl+PP1/pm29205377-58-74-75
    Average 90 stars, based on 1 article reviews
    selective inhibitor src family tyrosine kinases, pp1 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    10 μm src family kinase inhibitor pp1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine  (Millipore)
    90
    Millipore 10 μm src family kinase inhibitor pp1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine
    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of <t>PP1</t> (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.
    10 μm Src Family Kinase Inhibitor Pp1 (4 Amino 5 (4 Methylphenyl) 7 (T Butyl)pyrazolo D 3,4 Pyrimidine, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/src+family+kinase+inhibitor+pp1/src+inhibitor+pp2/pmc05866922-124-36-42
    Average 90 stars, based on 1 article reviews
    10 μm src family kinase inhibitor pp1 (4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo-d-3,4-pyrimidine - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of PP1 (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.

    Journal: Endocrine-Related Cancer

    Article Title: Targeting Src tyrosine kinase to enhance radioiodide uptake in breast cancer

    doi: 10.1530/ERC-24-0312

    Figure Lengend Snippet: Src inhibition inhibits PBF phosphorylation and restores RAIU. (A) MCF-7 (i) and MDA-MB-231 (ii) cells were treated with varying doses of PP1 (0–2 μM) for 24 h before PBF-pY174 and total PBF expression levels were determined by Western blot. (B) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. (C) Effect of 2 μM PP1 treatment on PBF-mediated RAIU repression in MCF-7 cells treated with ATRA and dexamethasone. (D) PBF-pY174 and total PBF expression levels following dasatinib dose response (0–2 μM) treatment for 24 h in MCF-7 (i) and MDA-MB-231 (ii) cells. (E) Effect of 1 nM dasatinib or 10 nM saracatinib treatment on PBF-repressed RAIU in MCF-7 (i) and MDA-MB-231 (ii) cells transiently co-transfected with NIS-MYC. n = 3 for all experiments. Error bars = SEM. * = P < 0.05, ** = P < 0.01, *** = P < 0.001.

    Article Snippet: Src family kinase inhibitors PP1 (Tocris, UK), dasatinib and saracatinib (Selleck Chemicals, USA) and NMT inhibitor (DDD85646; Drug Discovery Unit, University of Dundee) were dissolved in DMSO to a 10 mM stock concentration.

    Techniques: Inhibition, Phospho-proteomics, Expressing, Western Blot, Transfection